PSA Velocity Calculator

The PSA Velocity Calculator estimates the rate of change in prostate-specific antigen levels using multiple PSA test results and their dates. This tool helps men and doctors assess prostate cancer risk more accurately than a single test number. Whether you are tracking active surveillance, deciding on a biopsy, or monitoring routine health, this calculator clarifies your biological trends. It turns raw lab data into actionable health insights.

Enter the first PSA test result in ng/mL
Date of the first PSA test
Enter the second PSA test result in ng/mL
Date of the second PSA test
Enter the third PSA test result in ng/mL for more accurate calculation
Date of the third PSA test

How PSA Velocity Is Calculated

PSA Velocity measures the annual rate of change in your prostate-specific antigen levels. This calculation uses a linear slope method to identify significant trends rather than temporary daily fluctuations. By looking at the speed of change, doctors can often find aggressive cancers earlier than by looking at total PSA alone.

PSA Velocity = (PSA2 - PSA1) / Time in Years

Where:

  • PSA1 & PSA2 = Your test results
  • Time = Difference between test dates in years

To find your rate, first calculate the time difference between your tests in years. Next, subtract your first PSA value from your most recent one. Finally, divide the PSA change by the time difference. If you provide a third test result, the calculator averages the slopes between all points. This mathematical approach smooths out natural noise in your body to reveal the true biological trend.

What Your PSA Velocity Means

Your result reveals how fast your PSA levels are rising, which is often a better indicator of cancer danger than a single high number.

Low Risk (Under 0.35 ng/mL/year) suggests stable health typical of normal aging or BPH. In this range, you can usually continue routine annual screening without immediate concern.

Moderate Risk (0.35 to 0.75 ng/mL/year) falls into a cautionary gray zone. Here, doctors may suggest additional tests like an MRI or free PSA test to rule out hidden issues.

High Risk (Over 0.75 ng/mL/year) indicates a rapid rise often linked to aggressive, high-grade cancer. This result is a strong indicator that a prostate biopsy is necessary to confirm a diagnosis.

Important: This tool is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician regarding any medical condition.

To get the most accurate trends, keep your testing intervals consistent, ideally 12 to 24 months apart.